Tulathromycin Antibiotic Antifungal Directly From The Factory

Payment: T/T, L/C Product Origin: China Shipping Port: Beijing/Shanghai/Hangzhou Production capacity: 400kg/month Order(MOQ): 25kg Lead Time: 3 Working Days Storage condition: Stored in cool, dry place, room temperature. Package material: drum Package size: 25kg/drum Safety information: Not dangerous goods

Item	Specification
Appearance	White or almost white powder
Solubility	It is freely soluble in methanol, acetone, and methyl acetate, soluble in ethanol
Specific optical rotation	-22° to -26°
Identification	HPLC: retention time of major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the strandard preparation obtained as specified in the assay IR: IR spectrum is consistent with CRS
Water	≤2.5%
Residue on ignition	≤0.10%
Heavy metals	≤20ppm
Related substance	Total impurity ≤6.0% Individual impurity ≤3.0%
Bacterial endotoxin	< 2 EU
Assay (anhydrous substance)	95%-103%
Residual solvent	N-Heptane≤5000ppm Dichloromethane ≤600ppm
Assay	Content of C₄₁H₇₉N₃O₁₂: 95%-103% (On Anydrous substance)

Tulathromycin, is a broad-spectrum antibacterial agent with antibacterial activity against some gram-positive and Gram-negative bacteria. It especially sensitive to pathogens of respiratory diseases in cattle and pigs, such as Actinobacillus pleuropneumoniae, Pasteurella haemolyticus, Pasteurella haemorrhagica, histophilus sleep (Haemophilus sleep), Mycoplasma pneumoniae, Haemophilus parasuis, Bordetella bronchiseptica, etc. The pharmacokinetic characteristics of Tulathromycin are that after single dose administration, it is rapidly absorbed at the injection site, the effective blood concentration is maintained for a long time, the elimination is slow, the apparent distribution volume is large, the bioavailability is high, and the concentration in peripheral tissue is higher than that in plasma. Extensive tissue distribution and good cell permeability are important characteristics of Tulathromycin metabolism. Accumulation in immune cells is also an important feature of Tulathromycin. Tulathromycin inhibits bacterial protein synthesis by blocking the bacterial peptide transfer process. Due to some important defects of erythromycin, people need another drug to instead of erythromycin urgently. Tulathromycin is a new kind of macrolide semi synthetic antibiotic for animals. It has many advantages, such as low dosage, one-time administration, low residue, animal specific and so on. It not only has the advantages of macrolide drugs, but also has an ultra long half-life which is superior to other macrolide antibiotics. Base on the advantage of maintain effective therapeutic concentration in the body for a long time, it can achieve better bacteriostasis and sterilization. After extensive clinical application, tulathromycin has obvious therapeutic effect on respiratory diseases of cattle and pigs. Thanks for the excellent antibacterial activity of Tulathromycin like small dosage using, long half-life and one-time administration, it can be used widely. Tulathromycin is stronger than the macrolides widely used in the market currently, such as tylosin, tilmicosin and florfenicol. Which has huge potential applications. Attention to be paid that Tulathromycin is relatively safe, without carcinogenicity, teratogenicity and genotoxicity. It will not induce gene mutation, but may produce cardiotoxicity. Need to follow advise of veterinary.

Tulathromycin 217500-96-4 Antibiotic Antifungal

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