Mirabegron 223673-61-8 Inhibitor Neuronal signal

Synonyms: YM 178,N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)-2-(2-aminothiazol-4-yl)acetamide CAS No.: 223673-61-8 Quality: in house Molecular Formula:  C21H24N4O2S Formula Weight:  396.51

Products Details

Payment: T/T, L/C Product Origin: China Shipping Port: Beijing/Shanghai/Hangzhou Production capacity: 100kg/month Order(MOQ): 25kg Lead Time: 3 Working Days Storage condition: Stored in cool, dry place, room temperature. Package material: drum Package size: 25kg/drum Safety information:  Not dangerous goods

Item

Specification

Appearance White to off white powder

Identification

IR, HPLC
Water content NMT 0.5%
Residue on ignition NMT 0.1%
Heavy metal NMT 20ppm
Palladium content NMT 20ppm
Optical isomer NTM 0.5%
Related substance Z-168*: NMT 0.15%
  SC03610*: NMT 0.15%
  Any other unknown impurity: NMT 0.10%
  Total impurity: NMT 0.5%
2-(2-aminothianzol-4-yl) acetic acid NMT 0.1%
Residual solvent Methanol: NMT 0.3%
  Ethyl acetate: NMT 0.5%
  THF: NMT 0.072%
  Benzene: NMT 0.0002%
  Toluene: NMT 0.089%
Assay 98.0% - 102.0%
PSD D (0.5): 10μm - 30μm
  D (0.9): 20μm - 80μm
Mirabegron, is a beta-3 adrenergic receptor agonist, which stimulates the beta-3 adrenergic receptor and relaxes the detrusor smooth muscle, thereby increasing bladder capacity and is used to treat symptoms of overactive bladder (OAB), such as urge incontinence, urgency, and frequency. Its benefits are similar to antimuscarinic medication such as solifenacin or tolterodine.

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