Item | Specification |
Appearance | Is White or almost white, crystalline powder Is odorless or has a faint mercaptan-like odor. |
Identification | A) IR: Conforming B) The retention time of the major peak of the sample solution corresponds to that of the Standard solution as obtained in the Assay. |
Crystallinity | Meets the requirements |
Ph | 3.0-5.5 |
Water | 3.0%-6.0% |
Related Substances | |
Clindamycin B | ≤2.0% |
7-epiclindamycin | ≤4.0% |
Any other individual related compound | ≤1.0% |
Total of all related compound including Lincomycin | ≤6.0% |
Residual solvents Acetone | ≤5000ppm |
Assay | ≥830μg/mg |
Clindamycin is a semi-synthetic antibiotic with broad antibacterial spectrum and strong antibacterial activity. It has obvious antibacterial activity against Gram-positive bacteria, and can effectively kill Staphylococcus, anaerobic bacteria, pneumococcus and streptococcus.
It has active effects on pathogenic parasites such as Pneumocystis, Toxoplasma gondii and Plasmodium falciparum, and the adverse reactions are small.